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OpenUrlAbstract The primary analysis was on an intention to treat basis, with baseline values carried forward to replace missing values (one participant was not used in this analysis as she withdrew because of pregnancy). A secondary analysis focused on the outcomes of these dietary approaches in the most motivated subjects who provided complete data (baseline, two months, and six months). Analysis of variance showed that the test centre did not affect total weight loss in participants who completed. Attrition rates did not differ between centres, so we analysed data from all participants together. Baseline weight correlated with total weight loss (r = 0.33, P < 0.001) and was therefore used as a covariate in the analysis of weight loss over time, which uses repeated measures analysis of covariance. In the intention to treat analysis, we used ANOVA to examine differences between groups; where ANOVA indicated a significant group effect, we performed post hoc pairwise testing with Tukey's HSD (honestly significantly different) test. Before parametric testing, we assessed homogeneity of variance with Levene's statistic and tested for normal distribution; we used Welch's F statistic if variance of the dependent variable was not equal across groups. We analysed differences between participants who completed and withdrew with t tests for continuous variables (such as age) and χ2 for categorical variables (such as sex and diet group).
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Stollman N, Smalley W, Hirano I; AGA Institute Clinical Guidelines Committee. American Gastroenterological Association Institute Guideline on the Management of Acute Diverticulitis. Gastroenterology. 2015 Dec;149(7):1944-9. doi: 10.1053/j.gastro.2015.10.003. Epub 2015 Oct 8.
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